Invitrogen™ BLK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA577878

Catalog No. PIPA577878

Description

Positive Control: 293T, A431, Jurkat, Raji Predicted Reactivity: Mouse (83%), Rat (85%), Bovine (84%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

B-lymphoid tyrosine kinase (BLK) is a non-receptor tyrosine kinase that belongs to the Src family of kinases. BLK plays an important role in B-cell activation. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.

Specifications

• Antigen: BLK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BLK
• Gene Alias: B lymphocyte kinase; B lymphoid kinase; B lymphoid tyrosine kinase; Blk; BLK nonreceptor tyrosine kinase; BLK proto-oncogene, Src family tyrosine kinase; MGC10442; MODY11; p55-Blk; tyrosine-protein kinase Blk
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 640
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P51451
• Gene Symbols: BLK
• Immunogen: Recombinant protein encompassing a sequence within the center region of human BLK. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov