Invitrogen™ Blood Group ABH Antigen Monoclonal Antibody (HE-10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA544039

Catalog No. PIMA544039

Description

This antibody reacts specifically with malignant tissues.

Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Specifications

• Antigen: Blood Group ABH Antigen
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 15mM sodium azide; pH 8
• Host Species: Mouse
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Target Species: Human
• Product Type: Antibody
• Isotype: IgM

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin)
• Clone: HE-10
• Conjugate: Unconjugated
• Gene Alias: ABH; BG-H; BG-H1
• Immunogen: Mixture of erythrocytes of group A1 and glycoprotein fraction isolated from saliva of secretors with blood group A.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: 4°C, do not freeze
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov