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Blood Group Lewis a Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982433
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50-198-2433 100 μL
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Catalog No. 50-198-2433 Supplier Bioss Supplier No. BS12870R
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Description

Rabbit Polyclonal Antibody

The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

Specifications

Antigen Blood Group Lewis a
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene FUT3
Gene Accession No. P21217
Gene Alias 4-fucosyltransferase; alpha-(1,3/1,4)-fucosyltransferase; Blood group Lewis alpha-4-fucosyltransferase; CD174; FT3B; Fucosyltransferase 3; fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group); fucosyltransferase 3 (Lewis blood group); Fucosyltransferase III; FucT-III; FUT3; Galactoside 3(4)-L-fucosyltransferase; LE; Les; Lewis FT; Lewis Y
Gene Symbols FUT3
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Blood Group Lewis a.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2525
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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