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BLVRA Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
$151.31
Specifications
Antigen | BLVRA |
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Applications | Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Form | Liquid |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-156-7951
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Bethyl Laboratories, Inc
A304527AT |
20 μL |
Each of 1 for $151.31
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Description
The recommended shelf life for this product is 1 year from date of receipt.
Biliverdin reductase (BLVR) is a ubiquitously expressed, small cytoplasmic oxidoreductase that catalyzes the reduction of biliverdin to bilirubin. The first step of this process is catalyzed by heme oxygenase, an enzyme that converts heme to iron, carbon monoxide, and biliverdin. BLVR is unique among all enzymes to date in being dual pH/dual cofactor-dependent, as it requires NADH (pH 6.7) or NADPH (pH 8.7) as an electron donor. There are two isoforms of BLVR, biliverdin-IX alpha-reductase (BLVRA), the major component of human adult liver, and biliverdin-IX beta-reductase (BLVRB), found predomitly in fetal liver. The product of BLVR, bilirubin, is an important biological antioxidant, however it is also a neurotoxin and the cause of kernicterus. In addition to being an antioxidant, it inhibits kinase activity and the activity of enzymes such as protein kinase C and NADPH oxidase.Specifications
BLVRA | |
Polyclonal | |
Liquid | |
RUO | |
TBS with 0.1% BSA and 0.09% sodium azide | |
BLVRA, Biliverdin reductase A, EC 1.3.1.24, BVR A | |
BLVRA | |
IgG | |
Antigen affinity chromatography | |
Antibody |
Western Blot | |
Unconjugated | |
Rabbit | |
Human | |
P53004 | |
644 | |
Between 75 and 125 | |
Primary | |
4° C | |
BLVRA |
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