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Invitrogen™ BMI-1 Monoclonal Antibody (3E3)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA515919
Description
MA5-15919 targets BMI1 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human samples. The MA5-15919 immunogen is purified recombinant fragment of human BMI1 expressed in E. Coli. . MA5-15919 detects BMI1 which has a predicted molecular weight of approximately 37kDa.
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Specifications
BMI-1 | |
Monoclonal | |
Conc. Not Determined | |
ascites with 0.03% sodium azide | |
P25916, P35226 | |
BMI1 | |
Purified recombinant fragment of human BMI1 expressed in E. Coli. | |
RUO | |
12151, 648 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
3E3 | |
Unconjugated | |
BMI1 | |
AW546694; B lymphoma Mo-MLV insertion region 1; B lymphoma Mo-MLV insertion region 1 homolog; Bmi1; Bmi-1; BMI1 polycomb ring finger oncogene; BMI1 polycomb ring finger proto-oncogene; BMI1 proto-oncogene, polycomb ring finger; FLVI2/BMI1; flvi-2/bmi-1; murine leukemia viral (bmi-1) oncogene homolog; Pcgf4; Pcgf4 antibody; Polycomb complex protein BMI-1; polycomb group protein Bmi1; polycomb group ring finger 4; polycomb group RING finger protein 4; RING finger protein 51; RNF51; RP11-573G6.1 | |
Mouse | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG1 |
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