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Invitrogen™ BMI-1 Monoclonal Antibody (A11-C11)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA534897

Catalog No. PIMA534897


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Description

Description

Positive Control: Hela, NIH-3T3, SH-SY-5Y, human colon cancer tissue, mouse spleen tissue.

Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

BMI-1
Monoclonal
2 mg/mL
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
P25916, P35226
BMI1
Recombinant protein within mouse Bmi1 aa 1-324.
100 μL
Primary
Human, Mouse
Antibody
IgG2a
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
A11-C11
Unconjugated
BMI1
AW546694; B lymphoma Mo-MLV insertion region 1; B lymphoma Mo-MLV insertion region 1 homolog; Bmi1; Bmi-1; BMI1 polycomb ring finger oncogene; BMI1 polycomb ring finger proto-oncogene; BMI1 proto-oncogene, polycomb ring finger; FLVI2/BMI1; flvi-2/bmi-1; murine leukemia viral (bmi-1) oncogene homolog; Pcgf4; Pcgf4 antibody; Polycomb complex protein BMI-1; polycomb group protein Bmi1; polycomb group ring finger 4; polycomb group RING finger protein 4; RING finger protein 51; RNF51; RP11-573G6.1
Mouse
Affinity chromatography
RUO
12151, 648
-20°C, Avoid Freeze/Thaw Cycles
Liquid
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