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BMI-1 Monoclonal Antibody (DC9), Active Motif™
SDP

Catalog No. 501993132
Encompass
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50-199-3132 100 μg
50-199-3128 10 μg
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Catalog No. 50-199-3132 Supplier Active Motif Supplier No. 61089
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Description

Mouse Monoclonal Antibody

Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Specifications

Antigen BMI-1
Applications Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone DC9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene BMI1
Gene Accession No. P25916, P35226
Gene Alias AW546694; B lymphoma Mo-MLV insertion region 1; B lymphoma Mo-MLV insertion region 1 homolog; Bmi1; Bmi-1; BMI1 polycomb ring finger oncogene; BMI1 polycomb ring finger proto-oncogene; BMI1 proto-oncogene, polycomb ring finger; FLVI2/BMI1; flvi-2/bmi-1; murine leukemia viral (bmi-1) oncogene homolog; PCGF4; Pcgf4 antibody; Polycomb complex protein BMI-1; polycomb group protein Bmi1; polycomb group ring finger 4; Polycomb group RING finger protein 4; RING finger protein 51; RNF51; RP11-573G6.1
Gene Symbols BMI1
Host Species Mouse
Immunogen This BMI-1 antibody was raised against a recombinant protein corresponding to full-length mouse BMI-1.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12151, 648
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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