BMI-1 Mouse anti-Human, Mouse, Active Motif™
Mouse Recombinant Monoclonal Antibody
Manufacturer: Active Motif 91195
DescriptionComponent of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
|ChIP-sequencing, Western Blot|
|-20°C, Avoid Freeze/Thaw Cycles|
|140mM HEPES, 35mM sodium acetate with 30% glycerol, 70mM NaCl and 0.07% sodium azide; pH 7.5|
|AW546694; B lymphoma Mo-MLV insertion region 1; B lymphoma Mo-MLV insertion region 1 homolog; Bmi1; Bmi-1; BMI1 polycomb ring finger oncogene; BMI1 polycomb ring finger proto-oncogene; BMI1 proto-oncogene, polycomb ring finger; FLVI2/BMI1; flvi-2/bmi-1; murine leukemia viral (bmi-1) oncogene homolog; PCGF4; Pcgf4 antibody; Polycomb complex protein BMI-1; polycomb group protein Bmi1; polycomb group ring finger 4; Polycomb group RING finger protein 4; RING finger protein 51; RNF51; RP11-573G6.1|
|This antibody was raised against full length human BMI1-BMI1 polycomb ring finger oncogene.|
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