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Invitrogen™ BMI-1 Polyclonal Antibody, DyLight™ 650
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Catalog No. PIPA522845
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100 μL
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PIPA522845 100 μL
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Catalog No. PIPA522845 Supplier Invitrogen™ Supplier No. PA522845
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Description

Rabbit Polyclonal Antibody

Suggested positive control: human and mouse skeletal muscle. Immunogen sequence homology: primate, feline, chicken, bovine, rabbit, rat and Zebrafish protein (all 92%).

Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BMI-1
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.8 mg/mL
Conjugate DyLight 650
Formulation 50mM sodium borate with 0.05% sodium azide
Gene BMI1
Gene Accession No. P25916, P35226
Gene Alias AW546694; B lymphoma Mo-MLV insertion region 1; B lymphoma Mo-MLV insertion region 1 homolog; Bmi1; Bmi-1; BMI1 polycomb ring finger oncogene; BMI1 polycomb ring finger proto-oncogene; BMI1 proto-oncogene, polycomb ring finger; FLVI2/BMI1; flvi-2/bmi-1; murine leukemia viral (bmi-1) oncogene homolog; Pcgf4; Pcgf4 antibody; Polycomb complex protein BMI-1; polycomb group protein Bmi1; polycomb group ring finger 4; polycomb group RING finger protein 4; RING finger protein 51; RNF51; RP11-573G6.1
Gene Symbols BMI1
Host Species Rabbit
Immunogen A synthetic peptide made to an internal region (within residues 1-100) of human Bmi1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12151, 648
Target Species Human, Mouse
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG
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