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Invitrogen™ BMI-1 Recombinant Rabbit Monoclonal Antibody (BLR119H)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA544430

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Catalog No. PIMA544430


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Description

Description

Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.

Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

BMI-1
Recombinant Monoclonal
1 mg/mL
BBS with 0.09% sodium azide; pH 7.8-8.6
P25916, P35226
BMI1
Peptide representing a region between residue 250 and 300 of Human polycomb complex protein BMI1.
10 μL
Primary
Human, Mouse
Antibody
IgG
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
BLR119H
Unconjugated
BMI1
AW546694; B lymphoma Mo-MLV insertion region 1; B lymphoma Mo-MLV insertion region 1 homolog; Bmi1; Bmi-1; BMI1 polycomb ring finger oncogene; BMI1 polycomb ring finger proto-oncogene; BMI1 proto-oncogene, polycomb ring finger; FLVI2/BMI1; flvi-2/bmi-1; murine leukemia viral (bmi-1) oncogene homolog; Pcgf4; Pcgf4 antibody; Polycomb complex protein BMI-1; polycomb group protein Bmi1; polycomb group ring finger 4; polycomb group RING finger protein 4; RING finger protein 51; RNF51; RP11-573G6.1
Rabbit
Purified
RUO
12151, 648
4°C
Liquid
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