Invitrogen™ BMP-3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599399

Catalog No. PIPA599399

Description

Antibody detects endogenous levels of total BMP3.

The BMPs belong to the TGF-Beta superfamilyBMPs stimulate the production of bone matrix proteins and thereby alter stromal cell and osteoclast proliferation, a key step in bone marrow development. In addition to promoting ectopic bone and cartilage development, BMPs regulate the growth, differentiation, chemotaxis, proliferation, and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells, and neuronal cells. BMPs also play a role in dorsal/ventral patterning. BMP3, highly expressed in lung, ovary and small intestine, participates in cartilage and bone formation. BMP3 and BMP2 genes map to conserved regions between human and mouse.

Specifications

• Antigen: BMP-3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BMP3
• Gene Alias: 9130206H07; 9530029I04Rik; BMP; Bmp3; Bmp-3; BMP3A; BMP-3A; Bone morphogenetic protein; Bone morphogenetic protein 3; bone morphogenetic protein 3 (osteogenic); bone morphogenetic protein 3A; bone morphogenetic protein-3; osteogenin; PBMP3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 110075, 25667, 651
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P12645, P49002, Q8BHE5
• Gene Symbols: BMP3
• Immunogen: A synthesized peptide derived from human BMP3(Accession P12645), corresponding to amino acid residues R286-K336.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov