Invitrogen™ BMP-7 Monoclonal Antibody (164311)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA523877

Catalog No. PIMA523877

Description

In direct ELISAs, approximately 25% cross-reactivity with recombinant human (rh) BMP-6 is observed and no cross-reactivity with rhBMP-2, -3, -4, -5, or -8 is observed. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.

Specifications

• Antigen: BMP-7
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P18075
• Gene Symbols: Bmp7
• Immunogen: CHO-derived recombinant human BMP-7 Ser293-His431.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Paraffin), Neutralization, Western Blot
• Clone: 164311
• Conjugate: Unconjugated
• Gene: Bmp7
• Gene Alias: BMP; BMP7; BMP-7; bone moorphogenic protein-7; Bone morphogenetic protein; bone morphogenetic protein 7; bone morphogenetic protein 7 (osteogenic protein 1); bone morphogenetic protein 7 preproprotein; bone morphogenic protein 7; Eptotermin alfa; OP1; OP-1; Osteogenic protein 1; RP11-560A15.5
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 655
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid