Invitrogen™ BMP-7 Monoclonal Antibody (164313)

Catalog No.	Quantity
PIMA523878	100 μg

Catalog No. PIMA523878 Supplier Invitrogen™ Supplier No. MA523878

Description

Mouse Monoclonal Antibody

In ELISAs, this antibody shows approximately 25-50% cross-reactivity with recombinant human (rh) BMP-6 and no cross-reactivity with rhBMP-2, -3, -4, -5, or -8. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.

Specifications

• Antigen: BMP-7
• Applications: ELISA, Immunohistochemistry (Paraffin), Neutralization
• Classification: Monoclonal
• Clone: 164313
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 5% trehalose and No Preservative
• Gene: Bmp7
• Gene Accession No.: P18075
• Gene Alias: BMP; BMP7; BMP-7; bone moorphogenic protein-7; Bone morphogenetic protein; bone morphogenetic protein 7; bone morphogenetic protein 7 (osteogenic protein 1); bone morphogenetic protein 7 preproprotein; bone morphogenic protein 7; Eptotermin alfa; OP1; OP-1; Osteogenic protein 1; RP11-560A15.5
• Gene Symbols: Bmp7
• Host Species: Mouse
• Immunogen: CHO-derived recombinant human BMP-7 Arg292-His431.
• Purification Method: Protein A/G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 655
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1