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Invitrogen™ BMP-8B Polyclonal Antibody
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Catalog No. PIPA577881
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100 μL
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Catalog No. Quantity
PIPA577881 100 μL
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Catalog No. PIPA577881 Supplier Invitrogen™ Supplier No. PA577881
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Description

Rabbit Polyclonal Antibody

Positive Control: U87-MG, SK-N-SH, IMR32, SK-N-AS, human BMP8B-transfected 293T, mouse brain Predicted reactivity: Human (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

BMP-8B encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. BMP-8B may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1.
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Specifications

Antigen BMP-8B
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Bmp8b
Gene Accession No. P34820
Gene Alias BMP; BMP8; BMP-8; Bmp8b; BMP-8B; Bone morphogenetic protein; bone morphogenetic protein 8 (osteogenic protein 2); bone morphogenetic protein 8B; dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)); MGC131757; OP2; OP-2; Op3; Osteogenic protein 2
Gene Symbols Bmp8b
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human BMP8b. The exact sequence is proprietary.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 656
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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