Invitrogen™ BMP-8B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA131216

Catalog No. PIPA131216

Description

PA1-31216 detects BMP8 from rat, mouse, human samples.

BMP-8B encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. BMP-8B may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1.

Specifications

• Antigen: BMP-8B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Bmp8b
• Gene Alias: BMP; BMP8; BMP-8; Bmp8b; BMP-8B; Bone morphogenetic protein; bone morphogenetic protein 8 (osteogenic protein 2); bone morphogenetic protein 8B; dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)); MGC131757; OP2; OP-2; Op3; Osteogenic protein 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12164, 656, 679119
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Dot Blot, ELISA, Western Blot
• Concentration: 0.75 mg/mL
• Formulation: Tris glycine with 0.5% BSA, 30% glycerol and 0.02% sodium azide; pH 7.4-7.9
• Gene Accession No.: P34820, P55105
• Gene Symbols: Bmp8b
• Immunogen: synthetic peptide LQTLRAGDEGWLVL conjugated to KLH, corresponding to amino acids 184-197 of BMP8.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov