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Invitrogen™ BMP-8B Polyclonal Antibody
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Catalog No. PIPA131216
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100 μg
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PIPA131216 100 μg
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Catalog No. PIPA131216 Supplier Invitrogen™ Supplier No. PA131216
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Rabbit Polyclonal Antibody

PA1-31216 detects BMP8 from rat, mouse, human samples.

BMP-8B encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. BMP-8B may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1.
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Specifications

Antigen BMP-8B
Applications ELISA, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.67 mg/mL
Conjugate Unconjugated
Formulation Tris glycine with 0.5% BSA, 30% glycerol and 0.02% sodium azide; pH 7.4-7.9
Gene Bmp8b
Gene Accession No. P34820, P55105
Gene Alias BMP; BMP8; BMP-8; Bmp8b; BMP-8B; Bone morphogenetic protein; bone morphogenetic protein 8 (osteogenic protein 2); bone morphogenetic protein 8B; dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)); MGC131757; OP2; OP-2; Op3; Osteogenic protein 2
Gene Symbols Bmp8b
Host Species Rabbit
Immunogen Synthetic peptide taken within amino acid region 160-200 on human BMP8 protein.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12164, 656, 679119
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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