BMP4 Monoclonal Antibody (OTI1C2), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA803535

Catalog No. 50-167-9812

Description

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5′ untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Specifications

• Antigen: BMP4
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: BMP4
• Gene Alias: BMP2B, BMP2B1, MCOPS6, OFC11, ZYME
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 652
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Clone: OTI1C2
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P12644
• Gene Symbols: BMP4
• Immunogen: Human recombit protein fragment corresponding to amino acids 293-408 of human BMP4 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b