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Invitrogen™ BMPR1A Polyclonal Antibody
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Catalog No. PIPA518494
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100 μg
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Catalog No. Quantity
PIPA518494 100 μg
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Catalog No. PIPA518494 Supplier Invitrogen™ Supplier No. PA518494
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Description

Goat Polyclonal Antibody

This antibody is predicted to react with canine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

BMPR1A is a Type I member of the TGF beta receptor superfamily of transmembrane ser/thr kinases which phosphorylates intracellular SMADs in response to bone morphogenic proteins. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BMPR1A
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene BMPR1A
Gene Accession No. P36894, P36895
Gene Alias 10q23del; 1110037I22Rik; activin A receptor, type II-like kinase 3; activin receptor-like kinase 3; ACVRLK3; ALK3; ALK-3; AU045487; BMP type-1A receptor; BMP-2/BMP-4 receptor; Bmpr; Bmpr1a; BMPR-1A; BMPRIA; BMPR-IA; Bone morphogenetic protein 4 receptor; bone morphogenetic protein receptor type 1A; bone morphogenetic protein receptor type IA; bone morphogenetic protein receptor type-1A; bone morphogenetic protein receptor, type 1A; bone morphogenetic protein receptor, type IA; CD292; Serine/threonine-protein kinase receptor R5; SKR5
Gene Symbols BMPR1A
Host Species Goat
Immunogen Synthetic peptide sequence (KSDSDQKKSEN) corresponding to the internal amino acids of BMPR1A (aa 36-46).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12166, 657
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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