BMPR2 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-6001	100 μL

Catalog No. 50-198-6001 Supplier Bioss Supplier No. BS4237R

Description

Rabbit Polyclonal Antibody

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kDa and type II receptors of about 70-80 kDa. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.

Specifications

• Antigen: BMPR2
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: Bmpr2
• Gene Accession No.: Q13873
• Gene Alias: 2610024H22Rik; AL117858; AW546137; BB189135; BMP type II receptor; BMP type-2 receptor; BMP-2; BMPR2; BMPR-2; BMPR3; BMPRII; BMPR-II; BMR2; bone morphogenetic protein receptor type 2; Bone morphogenetic protein receptor type II; Bone morphogenetic protein receptor type-2; bone morphogenetic protein receptor, type II (serine/threonine kinase); bone morphogenic protein receptor, type II (serine/threonine kinase); BRK-3; Gm20272; POVD1; PPH1; T-ALK; type II activin receptor-like kinase; type II receptor for bone morphogenetic protein-4
• Gene Symbols: Bmpr2
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human BMPR2.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 659
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG