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Tocris Bioscience™ BMS 345541

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Quantity:
10 mg
50 mg
Description
BMS 345541 is a selective allosteric inhibitor of IKK (IC50 values are 0.3 and 4.0 μM for IKKβ and IKKα respectively). Exhibits no effect against a panel of 15 other kinases. Attenuates LPS-induced cytokine production in vitro and blocks NFκB dependent transcription in mice. Also suppresses joint destruction in a mouse model of arthritis.
Specifications
Specifications
Quantity | 10 mg |
Product Type | BMS 345541 |
Purity | >99% |
Molecular Weight (g/mol) | 291.78 |
Inhibitors | BMS 345541 |
For Research Use Only
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