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Tocris Bioscience™ BMS 345541
Selective allosteric inhibitor of IKK; anti-inflammatory
Supplier: Tocris Bioscience™ 4806/10
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Description
BMS 345541 is a selective allosteric inhibitor of IKK (IC50 values are 0.3 and 4.0 μM for IKKβ and IKKα respectively). Exhibits no effect against a panel of 15 other kinases. Attenuates LPS-induced cytokine production in vitro and blocks NFκB dependent transcription in mice. Also suppresses joint destruction in a mouse model of arthritis.Specifications
>99% | |
BMS 345541 | |
BMS 345541 |
10 mg | |
291.78 |
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