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Tocris Bioscience™ BMS 688521
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Catalog No. 497010 Shop All Novus Biologicals Products
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Catalog No. Quantity
49-701-0 10 mg
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Catalog No. 49-701-0 Supplier Tocris Bioscience™ Supplier No. 4970/10
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Description

Potent inhibitor of the LFA-1/ICAM interaction

BMS 688521 is a potent inhibitor of the LFA-1/ICAM-1 interaction (IC50 values are 2.5 and 78 nM in HUVEC adhesion and mouse specific adhesion assays respectively). Inhibits eosinophil accumulation in the lungs in a mouse allergic eosinophilic lung inflammation model.

Specifications

Chemical Name or Material 6-[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4,4]non-7-yl]-3-pyridinecarboxylic acid
CAS 893397-44-9
Quantity 10 mg
Molecular Formula C26H19Cl2N5O4
Formula Weight 536.37
Purity 98%
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