Invitrogen™ BMS1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA590414

Catalog No. PIPA590414

Description

Immunogen sequence: LSAEEEDSEN EEAIRKKLSK PSQVSSGQKL GPQNFIDETS DIENLLKEEE DYKEENNDSK ETSGALKWKE DLSRKAAEAF LRQQQAAPNL RKLIYGTVTE DNEEEDDDTL EELGGLFRVN QPDRECKHKA DSLDCSRFLV EAPHDWDLEE VMNSIRDCFV TGKWEDDKDA AKVLAEDEEL YGDFEDLETG DVHKGKSGPN TQNEDIEKEV KEEIDPDEEE SAKKKHLDKK RKLKEMFDAE YDEGESTYFD DLKGEMQKQA QLNRAEFEDQ DDEARVQYEG FRPGMYVRIE IENVPCEFVQ N; Positive Samples: A-431, HeLa, HepG2, MCF7, Mouse liver, Rat liver; Cellular Location: Nucleus, nucleolus.

BMS1 (Ribosome biogenesis protein BMS1 homolog) is a 1,282 amino acid protein encoded by the human gene BMS1. BMS1 is a nuclear protein that belongs to the BMS1/TSR1 family (BMS1 subfamily). BMS1 is believed to act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus. The 40S ribosomal subunit is an important member of the 80S ribosome complex, which also includes initiator tRNA and a 60S ribosomal subunit. The 80S ribosome is assembled by eukaryotic initiation factors (eIFs) at the initiation codon of mRNA in order to begin translation initiation. The joining of these ribosomal subunits requires eIF5B.

Specifications

• Antigen: BMS1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Bms1
• Gene Alias: AA408648; ACC; AU020092; AU043373; BB007109; BC030906; BMS1; BMS1 homolog, ribosome assembly protein; BMS1 homolog, ribosome assembly protein (yeast); BMS1 ribosome biogenesis factor; BMS1, ribosome biogenesis factor; Bms1l; BMS1-like, ribosome assembly protein; KIAA0187; mKIAA0187; ribosome assembly protein BMS1 homolog; Ribosome biogenesis protein BMS1 homolog
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 213895, 362426, 9790
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.93 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q14692
• Gene Symbols: Bms1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 600-900 of human BMS1 (NP_0555683).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG