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Invitrogen™ BNIP2 Polyclonal Antibody
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Catalog No. PA549988
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100 μL
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PA549988 100 μL
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Catalog No. PA549988 Supplier Invitrogen™ Supplier No. PA549988
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total BNIP2 protein.

BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BNIP2
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Bnip2
Gene Accession No. O54940, Q12982
Gene Alias 5730523P12Rik; Bcl-2 and E1B 19 kDa interacting protein; BCL2 interacting protein 2; BCL2/adenovirus E1B 19 kDa protein-interacting protein 2; BCL2/adenovirus E1B 19 kDa-interacting protein 2 beta; BCL2/adenovirus E1B 19kDa interacting protein 2; BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP2; BCL2/adenovirus E1B interacting protein 1, NIP2; BCL2/adenovirus E1B interacting protein 2; BNIP 2; BNIP2; BNIP-2; BNIP2beta; NIP2; Nip21; Nip2l
Gene Symbols Bnip2
Host Species Rabbit
Immunogen Synthesized peptide derived from C-terminal of human BNIP2.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12175, 663
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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