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BNIP3L Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501563614
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Catalog No. Quantity
50-156-3614 10 μL
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Catalog No. 50-156-3614 Supplier Bethyl Laboratories, Inc Supplier No. A302842AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse and Bovine

Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3a, and Nix (for Nip3-like protein X Bnip3L/Bnip3a/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis. Bnip3L interacts with and overcomes suppresses by Bcl-2 and Bcl-xL. Bnip3L is localized in mitochondria.

Specifications

Antigen BNIP3L
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene BNIP3L
Gene Accession No. O60238
Gene Alias BNIP3a, NIX
Gene Symbols BNIP3L
Host Species Rabbit
Immunogen Between 75 and 125
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 665
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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