Invitrogen™ Bone SialoProtein Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579424

Catalog No. PIPA579424

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - IHC: Human Osteosarcoma Tissue.

The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.

Specifications

• Antigen: Bone SialoProtein
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ibsp
• Gene Alias: BNSP; Bone sialoprotein 2; bone sialoprotein II; Bsp; BSP II; Bsp2; BSPII; BSP-II; Cell-binding sialoprotein; IBSP; integrin binding sialoprotein; integrin-binding sialoprotein; SP-II
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15891, 24477, 3381
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
• Gene Accession No.: P13839, P21815, Q61711
• Gene Symbols: Ibsp
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Bone Sialoprotein (17-34aa FSMKNLHRRVKIEDSEEN).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG