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Invitrogen™ Bone SialoProtein Polyclonal Antibody
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Catalog No. PIPA579425
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100 μg
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Catalog No. Quantity
PIPA579425 100 μg
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Catalog No. PIPA579425 Supplier Invitrogen™ Supplier No. PA579425
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: rat cartilage tissue, mouse cartilage tissue. IHC: mouse pancreas tissue, rat liver tissue.

The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Bone SialoProtein
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.01mg sodium azide, 0.01mg thimerosal
Gene Ibsp
Gene Accession No. P13839, Q61711
Gene Alias BNSP; Bone sialoprotein 2; bone sialoprotein II; Bsp; BSP II; Bsp2; BSPII; BSP-II; Cell-binding sialoprotein; IBSP; integrin binding sialoprotein; integrin-binding sialoprotein; SP-II
Gene Symbols Ibsp
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of mouse Bone Sialoprotein (305-324aa SYYKGHGYEGYEGQNYYYHQ).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15891, 24477
Target Species Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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