Invitrogen™ Bordetella pertussis Toxin Monoclonal Antibody (1280/204)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA183016

Catalog No. PIMA183016

Description

Mouse anti Bordetella Pertussis Toxin antibody, clone 1280/204 is reactive with Bordetella pertussis toxin in a simple ELISA. Reactivities with other organisms have not yet been determined.

B. pertussis has the ability to inhibit the function of the host's immune system. The toxin, known as pertussis toxin (or PTx), inhibits G protein coupling that regulates an adenylate cyclase-mediated conversion of ATP to cyclic AMP. The end result is phagocytes convert too much ATP to cyclic AMP, which can cause disturbances in cellular signaling mechanisms, and prevent phagocytes from correctly responding to an infection.

Specifications

• Antigen: Bordetella pertussis Toxin
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.2
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Bacteria
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunocytochemistry
• Clone: 1280/204
• Conjugate: Unconjugated
• Gene Alias: B. pertussis; PTx
• Immunogen: Native protein.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid