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Tocris Bioscience™ Bosutinib
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Catalog No. 436110
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Dual Src-Abl inhibitor; antiproliferative

Dual inhibitor of Abl and Src kinases (IC50 = 1.2 nM for Src in an enzymatic assay). Displays antiproliferative activity against chronic myelogenous leukemia (CML) cells and decreases the motility and invasion of breast cancer cell lines. Also exhibits potent antiproliferative activity in anchorage-independent, Src-transformed rat fibroblasts (IC50 = 100 nM). Displays selectivity for Src over non-Src family kinases such as growth factor receptor tyrosine kinases.

Chemical Identifiers

CAS 380843-75-4
Molecular Formula C26H29Cl2N5O3

Specifications

Quantity 10 mg
Formula Weight 530.45
Purity >99%
Molecular Weight (g/mol) 530.45
Chemical Name or Material Bosutinib

Safety and Handling

Recommended Storage Store at +4°C
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