Invitrogen™ BPNT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528168

Catalog No. PIPA528168

Description

Recommended positive controls: HeLaS3, mouse liver. Predicted reactivity: Mouse (93%), Rat (94%), Xenopus laevis (84%), Chicken (83%), Bovine (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.

Specifications

• Antigen: BPNT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Bpnt1
• Gene Alias: 3'(2'), 5'-bisphosphate nucleotidase 1; 3'(2'),5'-bisphosphate nucleotidase 1; Bisphosphate 3'-nucleotidase 1; BPNT1; BPntase; epididymis luminal protein 20; HEL20; PAP-inositol 1,4-phosphatase; PAP-inositol-1,4-phosphatase; PIP; Sal3; scHAL2 analogous 3; testicular tissue protein Li 29
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10380, 23827
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.7 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O95861, Q9Z0S1
• Gene Symbols: Bpnt1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human BPNT1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov