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Invitrogen™ BPNT1 Polyclonal Antibody
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Catalog No. PIPA528168
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100 μL
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PIPA528168 100 μL
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Catalog No. PIPA528168 Supplier Invitrogen™ Supplier No. PA528168
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Rabbit Polyclonal Antibody

Recommended positive controls: HeLaS3, mouse liver. Predicted reactivity: Mouse (93%), Rat (94%), Xenopus laevis (84%), Chicken (83%), Bovine (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BPNT1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.7 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Bpnt1
Gene Accession No. O95861, Q9Z0S1
Gene Alias 3'(2'), 5'-bisphosphate nucleotidase 1; 3'(2'),5'-bisphosphate nucleotidase 1; Bisphosphate 3'-nucleotidase 1; BPNT1; BPntase; epididymis luminal protein 20; HEL20; PAP-inositol 1,4-phosphatase; PAP-inositol-1,4-phosphatase; PIP; Sal3; scHAL2 analogous 3; testicular tissue protein Li 29
Gene Symbols Bpnt1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human BPNT1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10380, 23827
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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