BRAF Mouse anti-Human, Biotin, Clone: OTI3A7, liquid, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene TA700011

Catalog No. 50-167-7584

Description

B-raf belongs to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in the gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, maligt melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

Specifications

• Antigen: BRAF
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
• Gene Accession No.: P15056
• Gene Symbols: BRAF
• Immunogen: Protein expressed in 293T cell transfected with human BRAF expression vector
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: ELISA
• Clone: OTI3A7
• Conjugate: Biotin
• Gene: BRAF
• Gene Alias: B-RAF1, B-raf, BRAF1, NS7, RAFB1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 673
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid