BRAF Mouse anti-Human, Clone: OTI1D2, liquid, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene TA500844
DescriptionB-raf belongs to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in the gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, maligt melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide|
|B-RAF1, B-raf, BRAF1, NS7, RAFB1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot|
|Full length human recombit protein of human BRAF produced in HEK293T cell.|
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