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Invitrogen™ BRAP Polyclonal Antibody
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Catalog No. PIPA559145
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100 μL
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Catalog No. Quantity
PIPA559145 100 μL
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Catalog No. PIPA559145 Supplier Invitrogen™ Supplier No. PA559145
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SLVVIRLELA EHSPVPAGFG FSAAAGEMSD EEIKKTTLAS AVACLEGKSP GEKVAIIHQH LGRREMTDVI IETMKSNPDE LKTTVEERKS SEA Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 83%.

Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BRAP
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene BRAP
Gene Accession No. Q7Z569, Q99MP8
Gene Alias 3010002G07Rik; BRAP; BRAP2; BRCA1 associated protein; BRCA1-associated protein; galectin-2-binding protein; IMP; Impedes mitogenic signal propagation; renal carcinoma antigen NY-REN-63; RING finger protein 52; RING-type E3 ubiquitin transferase BRAP2; RNF52
Gene Symbols BRAP
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human BRAP. Recombinant protein control fragment (Product #RP-97663).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 687346, 72399, 8315
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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