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Invitrogen™ BRAP Polyclonal Antibody
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Catalog No. PIPA598573
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100 μg
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Catalog No. Quantity
PIPA598573 100 μg
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Catalog No. PIPA598573 Supplier Invitrogen™ Supplier No. PA598573
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Description

Rabbit Polyclonal Antibody

BRAP Polyclonal Antibody for Western Blot, ICC/IF, IHC (P), ELISA

Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BRAP
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 3.75 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene BRAP
Gene Accession No. Q7Z569
Gene Alias 3010002G07Rik; BRAP; BRAP2; BRCA1 associated protein; BRCA1-associated protein; galectin-2-binding protein; IMP; Impedes mitogenic signal propagation; renal carcinoma antigen NY-REN-63; RING finger protein 52; RING-type E3 ubiquitin transferase BRAP2; RNF52
Gene Symbols BRAP
Host Species Rabbit
Immunogen Recombinant Human BRCA1-associated protein (13-124AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 687346, 8315
Target Species Human, Rat
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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