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Invitrogen™ BRAP Polyclonal Antibody
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Catalog No. PIPA5103668
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100 μL
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PIPA5103668 100 μL
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Catalog No. PIPA5103668 Supplier Invitrogen™ Supplier No. PA5103668
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total BRAP.

Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BRAP
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene BRAP
Gene Accession No. Q7Z569
Gene Alias 3010002G07Rik; BRAP; BRAP2; BRCA1 associated protein; BRCA1-associated protein; galectin-2-binding protein; IMP; Impedes mitogenic signal propagation; renal carcinoma antigen NY-REN-63; RING finger protein 52; RING-type E3 ubiquitin transferase BRAP2; RNF52
Gene Symbols BRAP
Host Species Rabbit
Immunogen A synthesized peptide derived from human BRAP(Accession Q7Z569), corresponding to amino acid residues E556-K592.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8315
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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