BRAP Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A302681AT

Catalog No. 50-156-3204

Description

The recommended shelf life for this product is 1 year from date of receipt.

Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.

Specifications

• Antigen: BRAP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BRAP
• Gene Alias: BRAP2, IMP, RNF52, BRCA1-associated protein, RING finger protein 52, galectin-2-binding protein, impedes mitogenic signal propagation, renal carcinoma antigen NY-REN-63
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8315
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: Q7Z569
• Gene Symbols: BRAP
• Immunogen: Between 510 and 560
• Quantity: 10 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG