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BRAP Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501735666 Shop All Proteintech Group Inc Products
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50-173-5666 150 μL
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Catalog No. 50-173-5666 Supplier Proteintech Group Inc Supplier No. 274311AP150UL
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Rabbit Polyclonal Antibody

Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.

Specifications

Antigen BRAP
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene BRAP
Gene Accession No. Q7Z569
Gene Alias BRAP, BRAP2, BRCA1 associated protein, IMP, RING finger protein 52, RNF52
Gene Symbols BRAP
Host Species Rabbit
Immunogen BRAP Fusion Protein Ag26728
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8315
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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