BRD2 Mouse anti-Human, Clone:1H6B12, Abnova™

Catalog No.	Quantity
89-334-376	100 μg

Catalog No. 89-334-376 Supplier Abnova Corporation Supplier No. MAB17886

Description

Mouse monoclonal antibody raised against partial recombinant human BRD2.

This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene, but the full-length nature of some of these variants has not been determined. [provided by RefSeq]

Specifications

• Antigen: BRD2
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 1H6B12
• Conjugate: Unconjugated
• Description: bromodomain containing 2
• Dilution: ELISA (1:10000)
  Western Blot (1:100-1:500)
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene: BRD2
• Gene Alias: D6S113E, DKFZp686N0336, FLJ31942, FSH, FSRG1, KIAA9001, NAT, RING3, RNF3
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acids 227-364 of human BRD2.
• Quantity: 100 μg
• Gene ID (Entrez): 6046
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1