Invitrogen™ BRD2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100406

Catalog No. PIPA5100406

Description

Antibody detects endogenous levels of total BRD2.

This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatibility complex (MHC) class II region on chromosome 6p21. 3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene, but the full-length nature of some of these variants has not been determined.

Specifications

• Antigen: BRD2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BRD2
• Gene Alias: AW228947; Brd2; bromodomain containing 2; bromodomain-containing 2; bromodomain-containing protein 2; D17H6S113E; D6S113E; DADB-17J1.3; DKFZp686N0336; female sterile homeotic-related gene 1; Female sterile homeotic-related protein 1; FLJ31942; Frg-1; FSH; Fsrg1; Fsrg-1; Kiaa4005; KIAA9001; mKIAA4005; Nat; O27.1.1; Protein RING3; Really interesting new gene 3 protein; RING3; RING3 protein; Rnf3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6046
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P25440
• Gene Symbols: BRD2
• Immunogen: A synthesized peptide derived from human BRD2(Accession P25440), corresponding to amino acid residues Y40-L90.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov