Invitrogen™ BRD2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA515297

Catalog No. PIPA515297

Description

This antibody is predicted to react with bovine, mouse and rat based on sequence homology.

This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatibility complex (MHC) class II region on chromosome 6p21. 3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene, but the full-length nature of some of these variants has not been determined.

Specifications

• Antigen: BRD2
• Classification: Polyclonal
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P25440
• Gene Symbols: BRD2
• Immunogen: KLH conjugated synthetic peptide between 170-200 amino acids from the central region of human BRD2.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Gene: BRD2
• Gene Alias: AW228947; Brd2; bromodomain containing 2; bromodomain-containing 2; bromodomain-containing protein 2; D17H6S113E; D6S113E; DADB-17J1.3; DKFZp686N0336; female sterile homeotic-related gene 1; Female sterile homeotic-related protein 1; FLJ31942; Frg-1; FSH; Fsrg1; Fsrg-1; Kiaa4005; KIAA9001; mKIAA4005; Nat; O27.1.1; Protein RING3; Really interesting new gene 3 protein; RING3; RING3 protein; Rnf3
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 6046
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid