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Invitrogen™ BRD4 Recombinant Rabbit Monoclonal Antibody (BL-149-2H5)

Catalog No. PIMA544204
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Quantity:
20 μL
100 μL
Catalog No. Quantity
PIMA544204 20 μL
PIMA544203 100 μL
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Catalog No. PIMA544204

Supplier: Invitrogen™ MA544204

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Description

Rabbit Recombinant Monoclonal Antibody

Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.

BRD4, a ubiquitously expressed nuclear phosphoprotein, is a member of BET protein family. It is a human homolog of mouse MCAP and consists of 2 N-terminal bromodomains, a central ET-domain, and several kinase-like motifs in its N-terminus. It is expressed as 2 isoforms; the longer variant has a C-terminus region with a praline and glutamine-rich domains. BRD4 is a chromatin-binding protein whose expression is induced in response to growth stimuli. BRD4 acts at different stages of the cell cycle by interacting with proteins including RFC and SPA-1 and regulates cell growth. It also has a role in regulating chromosomal dynamics during mitosis. BRD4 functions as a cellular target for E2 protein of papillomavirus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BRD4
Applications ChIP sequencing (ChIP-seq), Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone BL-149-2H5
Concentration 100 μg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
Gene BRD4
Gene Accession No. O60885
Gene Alias Brd4; BRD4-NUT FUSION; Brd5; bromodomain containing 4; bromodomain-containing 4; bromodomain-containing 5; bromodomain-containing protein 4; bromodomain-containing protein 4; LOW QUALITY PROTEIN: bromodomain-containing protein 4; CAP; chromosome-associated protein; fsh-like protein; HUNK1; HUNKI; Mcap; mitotic chromosome-associated protein; Protein HUNK1; WI-11513
Gene Symbols BRD4
Host Species Rabbit
Immunogen Synthetic peptide representing a region between residues 1312 and 1362 of human bromodomain-containing protein 4.
Purification Method Purified
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23476
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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