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  6. BRD4 Recombinant Rabbit Monoclonal Antibody (BL-149-2H5), Bethyl Laboratories 

BRD4 Recombinant Rabbit Monoclonal Antibody (BL-149-2H5), Bethyl Laboratories

Catalog No. 501571261
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50-157-1261 100 μL
50-157-1262 20 μL
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Catalog No. 50-157-1261 Supplier Bethyl Laboratories, Inc Supplier No. A700004
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Description

Rabbit Recombit Monoclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For ICC, formaldehyde fixation is recommended. Permeabilization with Triton-X 100 is recommended for formaldehyde-fixed cells. For IHC, epitope retrieval with c

BRD4, a ubiquitously expressed nuclear phosphoprotein, is a member of BET protein family. It is a human homolog of mouse MCAP and consists of 2 N-terminal bromodomains, a central ET-domain, and several kinase-like motifs in its N-terminus. It is expressed as 2 isoforms; the longer variant has a C-terminus region with a praline and glutamine-rich domains.BRD4 is a chromatin-binding protein whose expression is induced in response to growth stimuli. BRD4 acts at different stages of the cell cycle by interacting with proteins including RFC and SPA-1 and regulates cell growth. It also has a role in regulating chromosomal dynamics during mitosis. BRD4 functions as a cellular target for E2 protein of papillomavirus.

Specifications

Antigen BRD4
Applications ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation
Classification Recombinant Monoclonal
Clone BL-149-2H5
Conjugate Unconjugated
Formulation BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
Gene BRD4
Gene Accession No. O60885
Gene Alias HUNK1
Gene Symbols BRD4
Host Species Rabbit
Immunogen Between 1312 and 1362
Purification Method Ion-exchange chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23476
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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