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Invitrogen™ BRD7 Polyclonal Antibody
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Catalog No. PIPA5100009
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PIPA5100009 100 μL
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Catalog No. PIPA5100009 Supplier Invitrogen™ Supplier No. PA5100009
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total BRD7.

BRD7 acts both as coactivator and as corepressor. For example, it activates the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. In addition, it is required for TP53-mediated cell-cycle arrest in response to oncogene activation. BRD7 promotes acetylation of TP53 at Lys-382, and thereby promotes efficient recruitment of TP53 to target promoters, inhibiting cell cycle progression from G1 to S phase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BRD7
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene BRD7
Gene Accession No. O88665, Q9NPI1
Gene Alias 75 kDa bromodomain protein; BP75; BRD7; bromodomain containing 7; bromodomain protein 75 kDa; bromodomain-containing 7; bromodomain-containing 7-like protein; bromodomain-containing protein 7; CELTIX1; NAG4; protein CELTIX-1; protein tyrosine phosphatase, non-receptor type 13 interacting protein; Ptpn13ip
Gene Symbols BRD7
Host Species Rabbit
Immunogen A synthesized peptide derived from human BRD7(Accession Q9NPI1), corresponding to amino acid residues I185-E235.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26992, 29117, 361374
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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