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BRD7 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501572498
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50-157-2498 10 μL
50-157-2497 100 μL
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Catalog No. 50-157-2498 Supplier Bethyl Laboratories, Inc Supplier No. IHC00664T
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Monkey, Gorilla, Chimpanzee and Northern white-cheeked gibbon

BRD7 acts both as coactivator and as corepressor. For example, it activates the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. In addition, it is required for TP53-mediated cell-cycle arrest in response to oncogene activation. BRD7 promotes acetylation of TP53 at Lys-382, and thereby promotes efficient recruitment of TP53 to target promoters, inhibiting cell cycle progression from G1 to S phase.

Specifications

Antigen BRD7
Applications Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene BRD7
Gene Accession No. Q9NPI1
Gene Alias Bromodomain-containing protein 7, 75 kDa bromodomain protein, Protein CELTIX-1, BRD7, BP75, CELTIX1
Gene Symbols BRD7
Host Species Rabbit
Immunogen Between 601 and 651
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29117
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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