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BRD7 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988007
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100 μL
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50-198-8007 100 μL
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Catalog No. 50-198-8007 Supplier Bioss Supplier No. BS7779R
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Description

Rabbit Polyclonal Antibody

BRD7 acts both as coactivator and as corepressor. For example, it activates the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. In addition, it is required for TP53-mediated cell-cycle arrest in response to oncogene activation. BRD7 promotes acetylation of TP53 at Lys-382, and thereby promotes efficient recruitment of TP53 to target promoters, inhibiting cell cycle progression from G1 to S phase.

Specifications

Antigen BRD7
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene BRD7
Gene Accession No. Q9NPI1
Gene Alias 75 kDa bromodomain protein; Bp75; Brd7; bromodomain containing 7; bromodomain protein 75 kDa; bromodomain-containing 7; Bromodomain-containing protein 7; CELTIX1; LOC100357102; NAG4; Protein CELTIX-1; protein tyrosine phosphatase, non-receptor type 13 interacting protein; Ptpn13ip
Gene Symbols BRD7
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human BRD7.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29117
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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