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Brefeldin A, Tocris Bioscience™

Catalog Number 12315
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Quantity:
5 mg
This item is not returnable. View return policy
20350-15-6
C16H24O4
280.36
MFCD00083258,MFCD12913297
KQNZDYYTLMIZCT-PNFJWZTBSA-N
brefeldin a, cyanein, decumbin, bfa
133640201
(1S,6S,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-1H,4H,6H,7H,8H,9H,11aH,12H,13H,14H,14aH-cyclopenta[f]oxacyclotridecan-4-one
C[C@H]1CCC\C=C\[C@@H]2C[C@H](O)C[C@H]2[C@@H](O)\C=C\C(=O)O1
This item is not returnable. View return policy
20350-15-6
C16H24O4
280.36
MFCD00083258,MFCD12913297
KQNZDYYTLMIZCT-PNFJWZTBSA-N
brefeldin a, cyanein, decumbin, bfa
133640201
(1S,6S,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-1H,4H,6H,7H,8H,9H,11aH,12H,13H,14H,14aH-cyclopenta[f]oxacyclotridecan-4-one
C[C@H]1CCC\C=C\[C@@H]2C[C@H](O)C[C@H]2[C@@H](O)\C=C\C(=O)O1

Description

Disrupts protein translocation to Golgi

Reversible inhibitor of protein translocation from the endoplasmic reticulum (ER) to the Golgi apparatus. Blocks binding of ADP-ribosylation factor (ARF1) to the Golgi apparatus and inhibits GDP-GTP exchange. Can be used to induce autophagy in mammalian cells. Also enhances CRISPR-mediated homology-directed repair (HDR) efficiency ∼2-fold when applied at 100 nM, in human induced pluripotent stem cells (iPSCs). Antifungal.
Quantity 5 mg
Formula Weight 280.36
Percent Purity >98%
Chemical Name or Material 1,6,7,8,9,11 Aβ,12,13,14,14 Aα-Decahydro-1β,13α-dihydroxy-6β-methyl-4 H-cyclopent[f]oxacyclotridecin-4-one

Safety and Handling

Recommended Storage Store at -20°C
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