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Brefeldin A, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
5mg
This item is not returnable. View return policy
20350-15-6
C16H24O4
280.364
KQNZDYYTLMIZCT-JBQJALHGSA-N
brefeldin a, cyanein, decumbin, bfa
133640201
(1S,7S,10E,12R,13R,15S)-12,15-dihydroxy-7-methyl-8-oxabicyclo[11.3.0]hexadeca-2,10-dien-9-one
CC1CCCC=CC2CC(CC2C(C=CC(=O)O1)O)O
This item is not returnable. View return policy
20350-15-6
C16H24O4
280.364
KQNZDYYTLMIZCT-JBQJALHGSA-N
brefeldin a, cyanein, decumbin, bfa
133640201
(1S,7S,10E,12R,13R,15S)-12,15-dihydroxy-7-methyl-8-oxabicyclo[11.3.0]hexadeca-2,10-dien-9-one
CC1CCCC=CC2CC(CC2C(C=CC(=O)O1)O)O

Disrupts protein translocation to Golgi

Reversible inhibitor of protein translocation from the endoplasmic reticulum (ER) to the Golgi apparatus. Blocks binding of ADP-ribosylation factor (ARF1) to the Golgi apparatus and inhibits GDP-GTP exchange. Can be used to induce autophagy in mammalian cells. Also enhances CRISPR-mediated homology-directed repair (HDR) efficiency ~2-fold when applied at 100 nM, in human induced pluripotent stem cells (iPSCs). Antifungal.

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Quantity 5mg
Formula Weight 280.36
Percent Purity >98%
Chemical Name or Material Brefeldin A

Recommended Storage : Desiccate at -20°C