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Invitrogen™ Brevican Polyclonal Antibody
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Catalog No. PIPA552477
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100 μL
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Catalog No. Quantity
PIPA552477 100 μL
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Catalog No. PIPA552477 Supplier Invitrogen™ Supplier No. PA552477
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ACYGDMDGFP GVRNYGVVDP DDLYDVYCYA EDLNGELFLG DPPEKLTLEE ARAYCQERGA EIATTGQLYA AWDGGLDHCS PGWLADGSVR YPIVTPSQRC GGGLPGVKTL FLFPNQTGFP NKHSRFNVYC FR Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 89%.

Brevican is the most abundant chondroitin sulfate proteoglycan in the extracellular matrix of the adult brain. It is a member of the lectican family of aggregating extracellular matrix proteoglycans that bear chondroitin sulfate (CS) chains. It is highly expressed in the central nervous system and is thought to stabilize synapses and inhibit neural plasticity. Brevican is secreted from astrocytes and neurons as a 145 kD core protein that bears up to three, covalently-linked, CS chains. It is also is secreted as a 145 kD core protein without CS chains. When cleaved by extracellular glutamyl endopeptidases, the ADAMTSs, a 55 kD N-terminal fragment is formed that contains the unique C terminal epitope EAMESE.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Brevican
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Bcan
Gene Accession No. Q96GW7
Gene Alias ALPBRE; Bcan; Behab; Brain-enriched hyaluronan-binding protein; brevican; brevican (brain specific proteoglycan in the aggrecan family); brevican core protein; Chondroitin sulfate proteoglycan 7; chondroitin sulfate proteoglycan BEHAB; CSPG7; UNQ2525/PRO6018
Gene Symbols Bcan
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Brevican. Recombinant protein control fragment (Product #RP-89912).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 63827
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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