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Invitrogen™ BRG1 Monoclonal Antibody (BRG-01)
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Catalog No. PIMA110062
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100 μg
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Catalog No. Quantity
PIMA110062 100 μg
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Catalog No. PIMA110062 Supplier Invitrogen™ Supplier No. MA110062
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Description

Mouse Monoclonal Antibody

This antibody recognizes an epitope within C-terminal part of human Brg1, a 205 kDa catalytic subunit of SWI2/SNF2-family chromatin-remodeling complexes.

Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair and DNA replication. Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes including those involved in interferon and stress response, immune cells differentiation, neurogenesis, cell cycle etc. and is absolutely necessary for mouse embryogenesis. Brg1 is also involved in cell growth arrest, senescence and tumour supression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BRG1
Applications Western Blot
Classification Monoclonal
Clone BRG-01
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene Smarca4
Gene Accession No. P51532
Gene Alias ATP-dependent helicase SMARCA4; b2b508.1Clo; b2b692Clo; BAF190; BAF190A; brahma protein-like 1; BRG1; brg-1; BRG1-associated factor 190A; BRM/SWI2-related gene 1; CSS4; FLJ39786; global transcription activator homologous sequence; homeotic gene regulator; HP1-BP72; hSNF2b; mitotic growth and transcription activator; MRD16; nuclear protein GRB1; protein brahma homolog 1; Protein BRG-1; RTPS2; SMARCA4; SNF2; Snf2b; SNF2beta; SNF2-beta; SNF2L4; SNF2LB; SNF2-like 4; sucrose nonfermenting-like 4; SW1/SNF; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4; SWI2; transcription activator BRG1
Gene Symbols Smarca4
Host Species Mouse
Immunogen Bacterially produced GST-fused protein representing 242 C-terminal amino acids of human Brg1.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6597
Target Species Human
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG2a
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