Invitrogen™ BRK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596704

Catalog No. PIPA596704

Description

Immunogen sequence: SRDNLLHQQM LQSEIQAMKK LRHKHILALY AVVSVGDPVY IITELMAKGS LLELLRDSDE KVLPVSELLD IAWQVAEGMC YLESQNYIHR DLAARNILVG ENTLCKVGDF GLARLIKEDV YLSHDHNIPY KWTAPEALSR GHYSTKSDVW SFGILLHEMF SRGQVPYPGM SNHEAFLRVD AGYRMPCPLE CPPSVHKLML TCWCRDPEQR PCFKALRERL SSFTSYENPT; Positive Samples: SW480, BT-474, MCF7, A-549, NIH/3T3, Mouse liver, Mouse kidney, Mouse testis, Rat kidney; Cellular Location: Cell projection, Cytoplasm, Membrane, Nucleus, ruffle.

Breast tumor kinase (Brk) is a non-receptor protein tyrosine kinase expressed in over 60% of breast carcinoma tissue samples and breast tumor cell lines. Brk is 80% identity to Sik (Src-related intestinal kinase) and exhibits the features of a novel non-receptor tyrosine kinase, including amino terminal SH3 and SH2 domains. Low levels of Brk transcripts have been identified in some human breast tumor cell lines but not in normal breast tissue.

Specifications

• Antigen: BRK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PTK6
• Gene Alias: ALT-PTK6; breast tumor kinase; BRK; deltam5; FLJ42088; protein tyrosine kinase 6; protein-tyrosine kinase 6; protein-tyrosine kinase BRK; Ptk6; PTK6 protein tyrosine kinase 6; Sik; SRC-related intestinal kinase; tks; Tksk; tyrosine kinase identified from skin; tyrosine-protein kinase BRK
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20459, 366275, 5753
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 4.37 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q13882, Q64434
• Gene Symbols: PTK6
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 222-451 of human PTK6 (NP_0059661).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov