Invitrogen™ BRK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528621

Catalog No. PIPA528621

Description

Recommended positive controls: HepG2. Predicted reactivity: Bovine (80%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Breast tumor kinase (Brk) is a non-receptor protein tyrosine kinase expressed in over 60% of breast carcinoma tissue samples and breast tumor cell lines. Brk is 80% identity to Sik (Src-related intestinal kinase) and exhibits the features of a novel non-receptor tyrosine kinase, including amino terminal SH3 and SH2 domains. Low levels of Brk transcripts have been identified in some human breast tumor cell lines but not in normal breast tissue.

Specifications

• Antigen: BRK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PTK6
• Gene Alias: ALT-PTK6; breast tumor kinase; BRK; deltam5; FLJ42088; protein tyrosine kinase 6; protein-tyrosine kinase 6; protein-tyrosine kinase BRK; Ptk6; PTK6 protein tyrosine kinase 6; Sik; SRC-related intestinal kinase; tks; Tksk; tyrosine kinase identified from skin; tyrosine-protein kinase BRK
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5753
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q13882
• Gene Symbols: PTK6
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 245 of Human Brk.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov