Invitrogen™ BRMS1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120312

Catalog No. PIPA5120312

Description

Positive test controls include: Mouse kidney, Mouse testis. The target is usually found in the following locations: Cytoplasm, Nucleus. Immunogen sequence: LEEVGAERAP EYTEPLGGLQ RSLKIRIQVA GIYKGFCLDV IRNKYECELQ GAKQHLESEK LLLYDTLQGE LQERIQRLEE DRQSLDLSSE WWDDKLHARG SSRSWDSLPP SKRKKAPLVS G.

This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.

Specifications

• Antigen: BRMS1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BRMS1
• Gene Alias: AV003220; AW554636; breast cancer metastasis suppressor 1; breast cancer metastasis-suppressor 1; Breast cancer metastasis-suppressor 1 homolog; BRMS 1; BRMS1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 107392, 25855, 293668
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 2.91 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q5M7T3, Q99N20, Q9HCU9
• Gene Symbols: BRMS1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 90-210 of human BRMS1 (NP_056214.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov