Tocris Bioscience™ BromoCatch™ Ligand, Alkyne

Catalog No.	Quantity
89-405-0U	50 μg

Catalog No. 89-405-0U Supplier Tocris Bioscience™ Supplier No. 8940/50U

Description

Clickable alkyne-functionalized covalent probe for BromoCatch-tagged proteins

BromoCatch™ Ligand, Alkyne is a covalent ligand engineered to irreversibly bind BromoCatch-tagged proteins via selective reaction with the E438C cysteine mutant of the Brd4-BD2 domain. Featuring a terminal alkyne appended to the BromoCatch Ligand scaffold, this ligand enables downstream modification through copper-catalyzed azide-alkyne cycloaddition (CuAAC). BromoCatch™ Ligand, Alkyne facilitates modular tagging of BromoCatch fusions with fluorophores, biotin, affinity tags, or functional moieties, offering a flexible platform for custom probe development. It enables site-specific protein labeling in vitro and is ideal for applications in chemical biology, proteomics, and multiplexed detection assays.

Please refer to this protocol for further information on how to use this product.

This product is part of an early adopter program .

BromoCatch™ is a trademark of Bio-Techne Corp.

Specifications

• Chemical Name or Material: (2R)-2-((6S)-4-(4-Acrylamidophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(2-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethoxy)ethyl)butanamide
• Quantity: 50 μg
• Target: BromoCatch Platform
• Molecular Formula: C33H40N6O5S
• Purity: 95%